JAMA Original Investigation Article
Journal of the American Medical Association, September 12, 2023
Retrospective Study from the UK Biobank, including 49,841 adults > 60 years without an initial diagnosis of dementia.
What’s Interesting about this article?
- Individuals in the study wore a wrist accelerometer to measure sedentary (sitting) time each day.
- These older adults resided in England, Scotland or Wales and were followed for 6.72 years. During this time 414 individuals were diagnosed with dementia.
- More time spent in sedentary behavior was significantly associated with a higher incidence of dementia.
- This is an extraordinarily large study group from one of the most respected data registries in the world.
- The retrospective study design does not allow a determination of whether this relationship is causal – i.e., that increased sitting time results in increased risk of dementia. However, it may be “associated with” the diagnosis of dementia.
- This study may add further weight to the adage that “sitting is the new smoking” in preventive medicine.
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